Revolution Plus Topical Solution for Cats, 2.8-5.5 lbs, (Gold Box)

• The product label states:

NOT FOR HUMAN USE. KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN.

In humans, Revolution Plus may be irritating to skin and eyes. Revolution Plus and selamectin topical solution contains isopropyl alcohol and the preservative butylated hydroxytoluene (BHT). Reactions such as hives, itching and skin redness have been reported in humans in rare instances after accidental dermal contact with selamectin topical solution. Individuals with known hypersensitivity to selamectin topical solution should use caution or consult a health care professional before applying this product to a cat. Wash hands after use and wash off any product in contact with the skin immediately with soap and water. If contact with eyes occurs, then flush eyes copiously with water; if wearing contact lenses, rinse the eyes first then move contact lenses and continue to rinse for 5-10 minutes and seek medical attention. In case of ingestion by a human, contact a physician immediately.

• Wearing disposable gloves is not mandatory (not mentioned on label), but can be considered when applying this medication.

• Wash your hands after handling any medication.

Agent for Prevention of Heartworm Disease; Treatment & Prevention of Flea Infestations; Treatment & Control of Tick Infestations; Treatment & Control of Ear Mite Infestations; Treatment & Control of Roundworm & Intestinal Hookworm Infections.

The combination product, selamectin and sarolaner, is used in cats to prevent heartworm infection and for treatment and control of flea, tick, and ear mite infestations. It is also approved for the treatment and control of roundworm and intestinal hookworm infections for one month. The FDA (U.S. Food & Drug Administration) has approved this drug for use in cats and kittens 8 weeks of age and older and weighing 2.8 pounds or more. The FDA does allow veterinarians to prescribe and use products containing this drug in different species or for other conditions in certain situations. You and your veterinarian can discuss why this drug is the most appropriate choice.

• Store this medication in the original package at a temperature less than 86°F (30°C).

• Keep away from heat, sparks, open flames, or other sources of ignition.

• If your veterinarian or pharmacist has made (compounded) a special formulation for your animal, follow the storage recommendations and expiration date for the product.

• Keep away from children and other animals.

• After applying, do not reapply for thirty (30) days unless your veterinarian specifically instructs you to do so. The Revolution® Plus product label indicates that the effectiveness of this combination product against heartworm infection after bathing has not been evaluated. However, bathing your cat 24 hours after application does not reduce the effectiveness of selamectin (an ingredient found in this combination product) against heartworm infection.

• Some animals may experience sticky fur, clumping of the fur, powder-like residue, or fur discoloration at the application site. These findings are temporary and do not affect your animal’s safety or the effectiveness of the medicine.

• Use of this drug may not be allowed in certain animal competitions. Check rules and regulations before entering your animal in a competition while this medication is being administered.

When used as directed on the label, cats typically tolerate this drug well.

Side effects (rare) that usually are not serious include:

• Hair loss and/or irritation at the site of application

• Itchiness

• Loss of appetite, vomiting, or diarrhea

• Red, irritated eyes (ie, conjunctivitis) or sneezing

• Low energy level

You don’t have to be overly concerned if you see any of these signs unless they are severe, worsen, or continue to be a problem. Contact your veterinarian if this happens.

Side effects that may be serious or indicate a serious problem include:

All are very rare, but may indicate an overdose or toxicity:

• Depression, lack of energy, or weakness

• Stumbling or collapse

• Seizures, tremors

• Dilated (big) pupils

• Excessive drooling

If you see any of these signs, contact your veterinarian immediately.